Press Release

Shire plc announces the pricing of its offering of US,000 million principal amount of Convertible Bonds

2 May 2007

Shire plc announces the pricing of its offering of US,000 million principal amount of Convertible Bonds (“Bonds”) due 2014 to be offered outside the United States and to non-US persons. The proceeds of the offering will provide refinancing on attractive terms for part of the bank facilities put in place for the recent acquisition of New River Pharmaceuticals Inc.

To view the full announcement please visit our website http://www.shire.com and go to the Latest News.

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