Press Release

Investor Relations

14 May 2007

The Company is restating its Consolidated Financial Statements for the year to December 31, 2005 to restate the value ascribed to in-process research and development and goodwill acquired as a result of the Transkaryotic Therapies, Inc acquisition on July 27, 2005. For further information see the Form 8-K filed with SEC on February 20, 2007.

The company intends to restate its consolidated financial statements for the year ended December 31, 2005 in its Annual Report on Form 10-K for the year ended December 31, 2006 which it anticipates filing in the week commencing February 26, 2007. Investors should look to the restated financial statements included within the Form 10-K for the year ended December 31, 2006 when they become available.

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