Press Release

Full Year 2007 results date notification – 21 February 2008

12 Feb 2008 - Basingstoke, UK and Philadelphia, US – 12 February 2008 – Shire plc (LSE: SHP, NASDAQ: SHPGY, TSX: SHQ), the global specialty biopharmaceutical company, will announce full year 2007 earnings on Thursday 21 February 2008.

Results press release will be issued at: 12:00 GMT / 07:00 EST
Investor meeting and conference call time: 14:00 GMT / 09:00 EST

Investor & Analyst meeting and conference call:
Matthew Emmens, Chief Executive Officer, Angus Russell, Chief Financial Officer, Mike Cola, President, Specialty Pharmaceuticals and Sylvie Grégoire, President, Human Genetic Therapies will host the investor and analyst meeting and conference call at 14:00 GMT/9:00 EST.

The meeting will take place at the offices of Deutsche Bank, Winchester House, 1 Great Winchester Street, London, EC2N 2DB.

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