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David Cameron has announced a three-part plan to get the UK's economy growing, following the announcement of the comprehensive spending review.
Addressing the CBI for the first time as prime minister, Cameron unveiled the government's growth strategy, saying he knew were economic growth and new jobs would come from.
He also announced £30bn will be invested into transport projects over the next four years.
And Cameron said the government will invest more than £200m over the next four years in technology and innovation centres bringing universtities and business together.
Pledging to create a "new economic dynamism", the prime minister said: "There are three parts to our plan.
"First, using all available policy levers to create the right framework for enterprise and business investment.
"Second, using our resources to get behind those industries where Britain enjoys competitive advantages.
"Third, using our power and muscle to make it easier for new companies and innovations to flourish."
The prime minister said the coalition will have "balanced the books" in five years time and that they no longer needed to "worry" about "sharp tax rises and huge interest rates".
Cameron also suggested a change in the government's policy of an annual limit on the number of non-EU migrants to the UK.
"Let me give you this assurance, as we control our borders and bring immigration to a manageable level, we will not impede you from attracting the best talent from around the world."
Announcing the UK's first national infrastructure plan, Cameron said it would "unlock" £200bn private and public sector investment to pay for it.
"We'll work with utility companies to get more investment in our energy, with construction companies on our roads, with the telecommunications industry on broadband," he said.
He added: "Even in this very constrained time, we will invest over £30bn in transport projects over the next four years."
Cameron also announced the government will provide up to £60m to meet the needs of offshore wind infrastructure for ports.
The Crown Estate will also work with ports and manufacturers to "realise the potential" of its sites.
Deputy prime minister Nick Clegg will also address the CBI's annual conference later on Monday.
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